Emva kweminyaka engaphezu kwemithathu yokulibaziseka, abaphandi balungiselela ukusungula ulingo lwezonyango olubalulekileyo olujolise ekuvavanyeni ukusebenza kokutshaya intsangu kunyango lwe-post-traumatic stress disorder (PTSD) kumagqala. Inkxaso-mali yolu phononongo ivela kwingeniso yerhafu evela kwintengiso yentsangu esemthethweni eMichigan.
I-Multidisciplinary Association for Psychedelic Drug Research (MAPS) ibhengeze kule veki ukuba i-US Food and Drug Administration (FDA) ivume isigaba sesibini sophononongo, apho i-MAPS ichaza kwi-press release "njenge-randomized, i-placebo-controlled control of 320 impi edla umhlala phantsi. abasebenzi abakhe basebenzisa intsangu kwaye banengxaki yoxinzelelo oluphakathi ukuya kolunzima emva koxinzelelo.
Umbutho uthe olu phononongo "lujonge ukuphanda uthelekiso phakathi kokuphefumla umxholo ophezulu we-THC omisiweyo we-Fried Dough Twists kunye ne-placebo cannabis, kwaye idosi yemihla ngemihla ihlengahlengiswa ngabathathi-nxaxheba ngokwabo." Uphononongo lujolise ekuboniseni iipatheni zokusetyenziswa ezenzeke kwilizwe lonke, kunye nokufunda "ukusetyenziswa kokwenyani kokuphefumla i-cannabis, ukuqonda iingenelo kunye nobungozi obunokubakho kunyango loxinzelelo lwasemva koxinzelelo."
I-MAPS ichaze ukuba le projekthi ibilungiselela iminyaka emininzi kwaye yabonisa ukuba kukho imiba emininzi ekuhlangatyezwene nayo xa ufaka isicelo sokwamkelwa kophando kwi-FDA, esandul' ukusonjululwa. Umbutho uthe, "Emva kweminyaka emithathu yothethathethwano ne-FDA, esi sigqibo sivula umnyango wophando lwexesha elizayo ngentsangu njengonyango kwaye izisa ithemba kwizigidi zabantu.
Upapasho lwe-MAPS luthi, "Xa kuqwalaselwa ukusetyenziswa kwentsangu ukunyanga uxinzelelo lwasemva koxinzelelo, iintlungu, kunye nezinye iimeko zempilo ezimandundu, ezi datha zibalulekile ekwaziseni izigulana, ababoneleli bezempilo, kunye nabathengi abadala, kodwa imiqobo elawulayo yenze yaba nentsingiselo. uphando ngokhuseleko kunye nokusebenza kakuhle kweemveliso zentsangu ezisetyenziswa kwiimarike ezilawulwayo zinzima kakhulu okanye azifumaneki.
I-MAPS yatsho ukuba kule minyaka idlulileyo, iphendule kwiileta ezintlanu zokunqunyanyiswa kwezonyango ezivela kwi-FDA, ezithintele inkqubela yophando.
Ngokutsho kombutho, "Ngomhla wama-23 ku-Agasti ka-2024, i-MAPS iphendule ileta yesihlanu ye-FDA malunga nokunqunyanyiswa kwezonyango kwaye yangenisa isicelo esisemthethweni sokusombulula iingxabano (FDRR) ukusombulula iyantlukwano eqhubekayo yesayensi kunye nolawulo kunye nesebe kwimiba emine engundoqo": " 1) idosi ecetywayo yeTHC yeemveliso zeFried Dough Twists zonyango, 2) ukutshaya njengendlela yolawulo, 3) ukufutha nge-elektroniki njengendlela ulawulo, kunye nesi-4) sokuqesha abathathi-nxaxheba abangazange bazame unyango lwe-cannabis. "
Umphandi ophambili wolu phononongo, ugqirha wengqondo uSue Sisley, uthe ulingo luya kunceda ukucacisa ngakumbi ukuba semthethweni kwesayensi yokusebenzisa intsangu yonyango ukunyanga ukuphazamiseka koxinzelelo lwasemva koxinzelelo. Ngaphandle kokunyuka kokusetyenziswa kwentsangu ngabaguli abanengxaki yoxinzelelo lwasemva koxinzelelo kunye nokubandakanywa kwayo kwiinkqubo ezininzi zonyango lwentsangu, uthe okwangoku kukho ukunqongophala kwedatha engqongqo yokuvavanya ukusebenza kwale ndlela yonyango.
USisley uthe kwisiteyitimenti: “EUnited States, izigidi zabantu baseMelika balawula okanye banyange iimpawu zabo ngokutshaya ngokuthe ngqo okanye nge-elektroniki kwintsangu yonyango. Ngenxa yokunqongophala kwedatha ekumgangatho ophezulu enxulumene nokusetyenziswa kwe-cannabis, uninzi lolwazi olufumanekayo kwizigulana kunye nabalawuli luvela kukuvalwa, kugxilwe kuphela kwimingcipheko enokubakho ngaphandle kokuqwalasela izibonelelo zonyango ezinokubakho. "
Kwindlela yam, abaguli abangamagqala babelane ngendlela intsangu yonyango enokubanceda ngayo ngcono ukulawula iimpawu zoxinzelelo lwasemva koxinzelelo kuneziyobisi zesintu, ”uqhubeke watsho. Ukuzibulala kwamagqala yingxaki engxamisekileyo yezempilo yoluntu, kodwa ukuba sityala imali kuphando olutsha lwezonyango ezibeka ubomi esichengeni iimeko ezifana noxinzelelo lwasemva koxinzelelo, le ngxaki inokusombulula.
USisley uthe inqanaba lesibini lophando lweklinikhi "liya kuvelisa idatha oogqirha abanjengam abanokusebenzisa ukwenza izicwangciso zonyango kunye nokunceda abaguli balawule iimpawu zoxinzelelo lwasemva koxinzelelo.
U-Allison Coker, intloko yophando lwe-cannabis kwi-MAPS, uthe i-FDA yakwazi ukufikelela kwesi sivumelwano kuba i-arhente yathi iya kuvumela ukuqhubeka kokusetyenziswa kwe-cannabis yonyango ekhoyo kunye nomxholo we-THC kwinqanaba lesibini. Nangona kunjalo, intsangu ye-elektroniki ene-nebulized ihlala ibambekile de i-FDA inokuvavanya ukhuseleko lwaso nasiphi na isixhobo sokuhambisa ichiza.
Ukuphendula kwiinkxalabo ezahlukeneyo ze-FDA malunga nokuqesha abathathi-nxaxheba abangazange bavezwe kunyango lwentsangu ukuba bathathe inxaxheba kwizifundo zonyango, i-MAPS ihlaziye iprotocol yayo ukuze ifune ukuba abathathi-nxaxheba babe “namava okuphefumla (ukutshaya okanye ukufutha) intsangu.
I-FDA iphinde yathandabuza ukuyilwa kophononongo oluvumela ukuba kulungiswe iidosi zokuzilungisa-ithetha ukuba abathathi-nxaxheba banokutya intsangu ngokweminqweno yabo, kodwa hayi ngaphaya kwesixa esithile, kwaye i-MAPS yala ukuthomalalisa kule ngongoma.
Isithethi se-FDA sixelele amajelo eendaba ukuba khange akwazi ukunika ulwazi oluthe kratya olukhokelele ekuvunyweni kovavanyo lwesigaba sesibini, kodwa waveza ukuba i-arhente “iyayibona imfuneko engxamisekileyo yokhetho olongezelelweyo lonyango lwezigulo ezimandundu zengqondo ezinje nge-post-traumatic. ukuphazamiseka koxinzelelo
Uphononongo luxhaswe ngemali yiNkqubo yeSibonelelo soPhando lwe-Michigan Veterans Cannabis, esebenzisa irhafu karhulumente yentsangu esemthethweni ukubonelela ngenkxaso-mali ye-FDA evunyiweyo yolingo lwezonyango olungenzi nzuzo “ukuphanda ukusebenza kwentsangu yonyango ekunyangeni izifo kunye nokuthintela igqala lokuzilimaza eUnited States. States.
Amagosa karhulumente karhulumente abhengeze i-13 yezigidi zeerandi kwinkxaso-mali yesi sifundo kwi-2021, eyinxalenye ye-20 yezigidi zeerandi kwizibonelelo. Ngaloo nyaka, enye i-7 yezigidi zeedola yabelwa kwiYunivesithi yaseWayne State Community Action kunye ne-Economic Opportunity Bureau, esebenzisana nabaphandi ukuba bafunde indlela intsangu yonyango inokunyanga ngayo izifo ezahlukeneyo zempilo yengqondo, kubandakanya ukuphazamiseka koxinzelelo lwasemva koxinzelelo, ixhala, ukuphazamiseka kokulala, ukudakumba, kunye noxinzelelo. utyekelo lokuzibulala.
Kwangelo xesha, ngo-2022, iMichigan Cannabis Administration iphakamise ukunikela ngeedola ezingama-20 ezigidi ngaloo nyaka kwiiyunivesithi ezimbini: iYunivesithi yaseMichigan kunye neYunivesithi yaseWayne State. Owangaphambili ucetywayo ukuba afunde ukusetyenziswa kwe-CBD ekulawuleni iintlungu, ngelixa lo mva wafumana inkxaso-mali yezifundo ezimbini ezizimeleyo: enye "yayiyiyokuqala i-randomized, elawulwayo, uvavanyo lwekliniki olukhulu" olujoliswe ekuphandeni ukuba ukusetyenziswa kwe-cannabinoids kunokuphucula i-prognosis. amagqala oxinzelelo lwasemva koxinzelelo olufumana unyango lwexesha elide (PE); Olunye uphononongo yimpembelelo yentsangu yonyango kwisiseko se-neurobiological ye-neuroinflammation kunye neengcinga zokuzibulala kumagqala anengxaki yoxinzelelo lwasemva koxinzelelo.
Umseki we-MAPS kunye nomongameli u-Rick Doblin uthe ngexesha lombutho ubhengeza ulingo lwezonyango olusandul' ulwamkelo lwe-FDA ukuba amagqala aseMelika “afuna ngokukhawuleza unyango olunokuphelisa iimpawu zawo ze-post-traumatic stress disorder (PTSD).
I-MAPS inebhongo ngokukhokela ekuvuleni iindlela ezintsha zophando kunye nokucela umngeni kwingcinga yemveli ye-FDA, "utshilo. Uphando lwethu lwentsangu lwezonyango lucela umngeni kwiindlela ze-FDA zokulawula amachiza ngokwesicwangciso kunye nexesha. I-MAPS iyala ukubeka esichengeni uyilo lophando ukuhambelana nokucinga okusemgangathweni kwe-FDA, ukuqinisekisa ukuba uphando lwentsangu lwezonyango lubonisa ukusetyenziswa kwayo kokwenyani.
Uphando oludlulileyo lwe-MAPS aluquki nje intsangu, kodwa kwakhona, njengoko igama lombutho libonisa, iziyobisi zengqondo. I-MAPS yenze i-spin off inkampani yophuhliso lwamachiza, i-Lykos Therapeutics (eyayisaziwa njenge-MAPS Philanthropy), ekwafake isicelo kwi-FDA ekuqaleni kwalo nyaka ukuze ivunywe ukusebenzisa i-methamphetamine (MDMA) ukunyanga ukuphazamiseka koxinzelelo lwasemva kokwenzakala.
Kodwa ngo-Agasti, i-FDA yalile ukuvuma i-MDMA njengonyango lwe-adjuvant. Olunye uphando olupapashwe kwi-Journal of Psychiatric Research lufumene ukuba nangona iziphumo zolingo lweklinikhi "zikhuthaza," uphando olongezelelweyo luyafuneka ngaphambi kokuba i-MDMA incedise unyango (MDMA-AT) ithathe indawo yeendlela zonyango ezikhoyo ngoku.
Amanye amagosa ezempilo athi emva koko, ngaphandle koku, le nzame isabonisa inkqubela phambili kwinqanaba likarhulumente. ULeith J. States, iGosa eliyiNtloko lezoNyango kwiOfisi kaSekela Nobhala wezeMpilo eUnited States wathi, “Oku kubonisa ukuba sihambela phambili, yaye izinto zenza ngokuthe ngcembe.
Ukongeza, kule nyanga, ijaji elaleleyo yoLawulo lokunyanzeliswa kweziyobisi (DEA) yasikhaba isicelo seKomiti yeVeterans Action Committee (VAC) ukuba ithathe inxaxheba kuvavanyo oluzayo lwesindululo sohlengahlengiso lwentsangu lolawulo lweBiden. I-VAC ichaze ukuba isiphakamiso "siyintlekisa yobulungisa" njengoko singabandakanyi amazwi abalulekileyo anokuthi achaphazeleke kwiinguqu zomgaqo-nkqubo.
Nangona i-DEA yazise uluhlu lwamangqina epotfoliyo ebandakanya wonke umntu ochaphazelekayo, i-VAC ithe “ayisaphumelelanga” ukuzalisekisa umsebenzi wayo wokuvumela abachaphazelekayo ukuba banike ubungqina. Umbutho wamagqala uthe oku kunokubonwa kwinto yokuba uJaji uMulroney wayihlehlisa inkqubo yokuchotshelwa kwetyala kwasekuqaleni kuka-2025 ngokuchanekileyo kuba i-DEA ibonelela ngolwazi olunganelanga malunga nesikhundla samangqina ayo akhethiweyo malunga nokuhlengahlengiswa kwentsangu okanye kutheni kufuneka bathathelwe ingqalelo ngabachaphazelekayo. .
Kwangelo xesha, iNkongolo yase-US iphakamise umthetho oyilwayo omtsha we-Senate kule nyanga ojolise ekuqinisekiseni intlalo-ntle yamagqala athe achanabeka kwiikhemikhali ezinokuba yingozi ngexesha leMfazwe ebandayo, kubandakanya i-hallucinogens efana ne-LSD, i-nerve agents, kunye nerhasi yemostade. Le nkqubo yovavanyo oluyimfihlo yaqhutywa ukusuka ngo-1948 ukuya kowe-1975 kwiziko lomkhosi eMaryland, ibandakanya izazinzulu zangaphambili zamaNazi ezilawula ezi zinto kumajoni aseMelika.
Kutshanje, umkhosi wase-US utyale izigidi zeedola ekuphuhliseni uhlobo olutsha lwamayeza anokubonelela ngezibonelelo zempilo yengqondo ezikhawulezayo njengamachiza esintu engqondo, kodwa ngaphandle kokuvelisa iziphumo ze-psychedelic.
Amagqala adlale indima ephambili ekumiselweni ngokusemthethweni kwentsangu yonyango kunye nentshukumo yangoku yokuguqulwa kweziyobisi ngokwengqondo kurhulumente nakwinqanaba lomdibaniso. Ngokomzekelo, ekuqaleni kwalo nyaka, i-Veterans Service Organisation (VSO) ikhuthaze amalungu eCongress ukuba enze uphando ngokukhawuleza malunga neenzuzo ezinokuthi zifumane unyango lwe-psychedelic kunye nentsangu yonyango.
Ngaphambi kwezicelo ezenziwe yimibutho efana ne-American Iraq kunye ne-Afghanistan Veterans Association, i-American Overseas War Veterans Association, i-American Disabled Veterans Association, kunye neProjekthi yaMajoni aKhubazekileyo, eminye imibutho yagxeka iSebe leMicimbi yamagqala (VA) ngokuba " kade” kuphando lwentsangu yezonyango kunyaka ophelileyo kudliwanondlebe lombutho weNkonzo yamagqala.
Phantsi kobunkokheli bezopolitiko zaseRiphabhlikhi, iinzame zokuguqula zikwabandakanya ibhili yeziyobisi zengqondo exhaswa yiRiphabhlikhi Party kwiCongress, egxile ekufikeleleni kumagqala, utshintsho kwinqanaba likarhulumente, kunye nothotho lweendibano zovavanyo lokwandisa ukufikelela kwiziyobisi zengqondo.
Ukongeza, i-Wisconsin Republican Congressman uDerrick Van Orden ungenise i-congressional psychedelic bill drug, ethe yaphononongwa yikomiti.
U-Van Oden ukwangumcebisi we-bipartisan ejolise ekuboneleleni ngenkxaso-mali yeSebe lezoKhuselo (DOD) ukuqhuba iimvavanyo zeklinikhi malunga nonyango lwamachiza athile e-psychedelic kubasebenzi basemkhosini abasebenzayo. Olu hlaziyo lutyikitywe ukuba lube ngumthetho nguMongameli uJoe Biden phantsi kwesihlomelo kuMthetho woGunyaziso lweSizwe loKhuselo wowama-2024 (i-NDAA).
Ngo-Matshi walo nyaka, iinkokeli zenkxaso-mali ye-congressional nazo zibhengeze isicwangciso senkcitho esibandakanya izibonelelo ze-10 yezigidi zeedola ukukhuthaza uphando ngamachiza e-psychedelic.
NgoJanuwari walo nyaka, iSebe leMicimbi yeMicimbi yamagqala likhuphe isicelo esahlukileyo esicela uphando olunzulu malunga nokusetyenziswa kweziyobisi zengqondo ukunyanga ingxaki yoxinzelelo lwasemva koxinzelelo kunye nokudakumba. Ngo-Okthobha odlulileyo, isebe liqalise i-podcast entsha malunga nekamva lezempilo zamagqala, kunye nesiqendu sokuqala soluhlu olugxininise kunyango lwamachiza e-psychedelic.
Kwinqanaba likarhulumente, irhuluneli yaseMassachusetts isayine umthetho oyilwayo ngo-Agasti ojolise kumagqala, kubandakanywa nezibonelelo zokuseka iqela elisebenzayo leziyobisi ze-psychedelic ukuba lifunde kwaye lingenise iingcebiso malunga neenzuzo zonyango ezinokubakho zezinto ezifana ne-psilocybin kunye ne-MDMA.
Ngeli xesha, eCarlifonia, abenzi bomthetho barhoxile ekuqwalaseleni umthetho oyilwayo we-bipartisan ngoJuni owawuza kugunyazisa iprojekthi yokulinga ukubonelela ngonyango lwe-psilocybin kumagqala kunye nabaphenduli bexesha likaxakeka.
Ixesha lokuposa: Nov-26-2024