Kutheni i-thc iphakamile kwaye i-CBD ayi?

I-thc, i-CBD, i-cannabinoids, iziphumo zengqondo-kusenokwenzeka ukuba ukhe wakuva okungenani izibini zala magama ukuba uzama ukuqonda i-thc, i-CBD, kunye nomahluko phakathi kwawo. Mhlawumbi ukhe wadibana nenkqubo ye-endocannabnabwanaid, ii-receptors ze-cannabicoid, kunye ne-terpenes. Kodwa yintoni kanye kanye?

Ukuba ufuna indlela yokuqonda ukuba kutheni iimveliso ze-thc zikufumanela iimveliso eziphakamileyo kwaye ze-CBD azinanto kwaye bakwenzayo nge-endocannabids, wamkelekile, ukwindawo elungileyo.

I-cannabinoids kunye nendima ye-ECS

Ukuqonda i-thc vs ye-ths kunye nendlela esisichaphazela ngayo, kufuneka siqonde inkqubo ye-gondocannabnab (i-ECS), enceda umzimba ophambili kwizinto eziphezulu eziphambili: Abamkeli zimolekyuli zibopha; Nee-enzymes eziqhekeza.

Intlungu, uxinzelelo, inkanuko, amandla imetabolism, umsebenzi we-Cardiovascular, uMvuzo kunye nenkuthazo, ukuvelisa kunye nokulala, kunye nokulala zinefuthe lemisebenzi ye-ECNABInoids enefuthe kwi-ECS. Izibonelelo zezempilo ezinokuba zininzi kwaye zibandakanya ukuncitshiswa kwe-incofetion kunye nolawulo lwe-Nuseuse.

Iyenza ntoni i-thc

Esona sityalo sikhulu nesisaziwayo esiziswe kwisityalo se-cannabis yiTetrarahdrocannal (thc). Iyenza i-Callptor ye-CB1, icandelo le-ECS kwingqondo elawula ukunxila. Ukuxinena kwe-thc kubonisiwe ukonyusa ukuhamba kwegazi kwi-cortix ephambili, indawo yengqondo enoxanduva lokuthatha izigqibo, ingqwalaselo, izakhono zemoto, kunye neminye imisebenzi yolawulo. Uhlobo ngqo lwemiphumo ye-thc kule misebenzi iyahluka emntwini.

Xa i-thc ibophelelane kwi-CB1 Reppers, ikwabangela iimvakalelo ze-euphoria kwi-FORY DONI. I-cannabis icofa indlela yengqondo yengqondo, eyenza sizive silungile, kwaye yonyusa amathuba ethu kwakhona kwixesha elizayo. Isiphumo se-thc kwiNkqubo yeMivuzo yeBhola yeBrain yeyona nto iphambili kumandla e-cannabis ye-cannabis yokuvelisa imvakalelo yokunxiba kunye ne-euphoria.

Yenziwa yi-CBD

I-thc ikude nesona sithako kwi-cannabis enefuthe ngqo kwingqondo. Owona mkhwa ungabonakaliyo inesitenadiol (i-CBD), eyesibini i-cannabinoid eninzi efumaneka kwisityalo se-cannabis. I-CBD ihlala igxothwa njenge-non-psychoacking kodwa oku kuyalahlekisa kuba nayiphi na into enefuthe ngqo emsebenzini yengqondo yingqondo. Ngokuqinisekileyo i-CBD ngokuqinisekileyo idala imiphumo yengqondo xa inxibelelana nengqondo kunye nenkqubo ye-nerint ye-nevous, njengoko kuxelwe ukuba inamandla amakhulu kunye ne-anti-castries.

Ke ngelixa i-CBD yeyokwenza ingqondo yengqondo, ayisiyotyhefu. Oko kukuthi, ayikufumani phezulu. Kungenxa yokuba i-CBD imbi kakhulu ekusebenzeni kwe-CB1 i-CB1. Ngapha koko, ubungqina bubonisa ukuba kuyiphazamisa imisebenzi ye-CB1, ngakumbi phambi kwe-thc. Xa i-thc ne-CBD isebenza kunye ukuba ichaphazele umsebenzi we-CB1, abasebenzisi bathanda ukuziva benobume obungaphezulu, i-nuested ephezulu kwaye banethuba elingaphantsi lokufumana i-paranoia xa i-CBD ingekho. Kungenxa yokuba i-thc iyenza i-CB1 Receptor, ngelixa i-CBD ithintele.

I-CBD kunye ne-thc inxibelelana njani

Ngamafutshane, i-CBD ingakhusela ngokuchasene nokungakhathali kwengqondo ehambelana no-Orbuvation kwi-thc. Uphando luka-2013 olupapashwe kwijenali ye-psychophaphacondocology iqhutywa ngabathathi-nxaxheba kwaye yafumanisa ukuba abo banikwe i-CBD kusetyenziswe i-thb ngaphandle kokuba i-CBD ingaphezulu kwe-CBD i-CBD ikhuphe i-CBD ye-curb ye-tifitication i-curb i-curb i-cindelity ye-CBD ingaphengululi.

Ngapha koko, ngo-2013 malunga nezifundo ezimalunga ne-1,300 ezipapashwe kwiijenali zesayensi zifumanise ukuba "i-CBD inokuchasa imiphumo emibi ye-thc." Uphengululo lukwachaza imfuno yophando ngakumbi kwaye ujonge iziphumo ze-CBD kwi-thc entywila kwimo yendalo yehlabathi. Kodwa idatha ekhoyo icacile ukuba i-CBD ihlala icetyiswa njenge-antidote kwabo balele kakhulu i-thc kwaye bazifumana bexinekile.

I-cannabinoids inxibelelana neenkqubo ezininzi emzimbeni

I-thc ne-CBD ibophe ezinye iithagethi eziqela emzimbeni. I-CBD, umzekelo, ubuncinci iisayithi ezili-12 zesenzo kwingqondo. Kwaye apho i-CBD ingalungelelanisa imiphumo ye-thc ngokuthengisa i-receptors ye-CB1, inokuba nezinye iziphumo kwi-thtabolism kwiindawo ezahlukeneyo zesenzo.

Ngenxa yoko, i-CBD isenokungasoloko ithintele okanye ilungelelanise imiphumo ye-thc. Ingaphucula ngokungqalileyo izibonelelo ezilungileyo zezonyango. I-CBD inokuthi, umzekelo, ukuphucula ukukhululeka kwe-thc I-thc inokwenzeka zombini i-antiolmatory kunye ne-auroproprocectivent ye-antisoproidant, ubukhulu becala ngenxa yokuvula ii-receptors zayo kwindawo ye-CB1 kwindawo yolawulo lwentlungu.

Isifundo ukusuka ngo-2012 satyhila ukuba i-CBD inxibelelana ne-alpha-3 (α3) ye-gelycine, ibaluleke kakhulu kwi-Plycine kwiPine, ukucinezela iintlungu ezingapheliyo kunye nokuvuvukala. Ngumzekelo wento ebizwa ngokuba yi-enatisas, apho amabala e-cannabis asebenza kunye) ukuze ihlale inesiphumo esiphezulu kunokuba siphumile ngokwahlukeneyo.

Kodwa nkqu nokudibana oku akucacanga ngokupheleleyo. Kwisifundo sikaFebruwari ka-2019, abaphandi bafumanise ukuba iidosi ezisezantsi ze-CBD ziphucule i-ityhefu ye-THC, ngelixa iidosi eziphezulu ze-CBD zinciphise iziphumo ezinxilisayo ze-thc.

I-Terpenes kunye nePerpedis

Kunokwenzeka ukuba kunokwenzeka ukuba ezinye zeziphumo ebezingasekelweni ze-cannabis (ezinjenge-Couch-lock) zinokuba zincinci kakhulu ukuba zenze nge-thc ngokwayo, kodwa endaweni yoko, igalelo le molekyuli engaphantsi. Imichiza yemichiza ebizwa ngokuba yiTerpenes inike i-cannabis ye-cannabis yayo kunye nee-aromas. Zifumaneka kwizityalo ezininzi-njenge-lavender, i-bark yomthi, kunye ne-hops-kwaye ibonelele nge-oils efanelekileyo. I-Gerts, elilolona qela likhulu le-phytochemicals eyaziwayo e-Cannabis, ikwangqinile ukuba yinxalenye yefuthe elibalulekileyo. Ayisiyo kuphela i-tertynes ​​i-cannabis eyahlukileyo kunye nevumba levumba, kodwa ikwabonakala ngathi ixhasa ezinye iimolekyuli ze-cannabis ekuveliseni iziphumo zomzimba kunye nezonyango.

Okukwintsusa

I-Cannabis sisityalo esintsonkothileyo ngophando oluncinci olukhoyo kwimiphumo yalo kunye nokudibana komzimba womntu - kwaye siqala ukunxibelelana neendlela zethu zokudibana ukuze sitshintshe indlela esivakalelwa ngayo.